4-Nitrophenyl α-D-galactopyranoside
CAS No. 7493-95-0
4-Nitrophenyl α-D-galactopyranoside ( PNP-alpha-D-Gal; PNP-α-D-Gal )
Catalog No. M27057 CAS No. 7493-95-0
4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) is an artificial substrate of 4-nitrophenyl (pNP) glycopyranoside for detecting α-galactosidase activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Name4-Nitrophenyl α-D-galactopyranoside
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NoteResearch use only, not for human use.
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Brief Description4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) is an artificial substrate of 4-nitrophenyl (pNP) glycopyranoside for detecting α-galactosidase activity.
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Description4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) is an artificial substrate of 4-nitrophenyl (pNP) glycopyranoside for detecting α-galactosidase activity. The amount of released pNP is significantly increased when 4-Nitrophenyl α-D-galactopyranoside is used as substrates.(In Vitro):Using 4-nitrophenol (pNP)-glycopyranosides as pseudosubstrates, the amount of liberated pNP from the 4-Nitrophenyl α-D-galactopyranoside is significantly higher than that from the other pNP-glycopyranosides at pH 4.0 whereas no activity was detected at pH 7.0. The digestion assays using pNP glycopyranosides as artificial substrates show that yielding liberated galactose residues from 4-Nitrophenyl α-D-galactopyranoside mainly at pH 4.0, i.e. the pH level where yield threshold is decreased at most.
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SynonymsPNP-alpha-D-Gal; PNP-α-D-Gal
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PathwayOthers
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TargetOther Targets
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RecptorAlkyl-Chain; Non-cleavable
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Research Area——
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Indication——
Chemical Information
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CAS Number7493-95-0
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Formula Weight301.3
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Molecular FormulaC12H15NO8
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Purity>98% (HPLC)
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Solubility——
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SMILESO[C@@H]1[C@H](O)[C@@H](O)[C@@H](OC2=CC=C([N+]([O-])=O)C=C2)O[C@@H]1CO
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.
molnova catalog
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